Ophthalmic suspensions containing polymers often form sticky droplets at nozzle tips during filling, creating exterior bottle neck contamination and cap sealing defects. Here is how Vedax solved the problem.
Positive Pneumatic Shutoff Dispensing Needles
Replacing open nozzles with internal needle-actuated positive shutoff tips eliminated droplet hang-up instantaneously upon dose completion.
Viscosity-Matched Hydrodynamic Geometry
The internal needle seat was CFD-modeled to prevent fluid shear thinning and product crystallization around the nozzle orifice.
Validation & Cleanability
The system achieved 100% cleanability in automated CIP cycles, validated by riboflavin fluorescence rinse testing.